Case Report: Locally Acquired Leptospirosis in a Minnesota Boy and His Dog

Author:

Thielen Beth K.1,Holzbauer Stacy23,Templen Bethany4,Schafer Ilana J.5,Artus Aileen5,Galloway Renee5,Ireland Malia2,Femrite Tanya6,Schleiss Mark R.1

Affiliation:

1. Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota;

2. Minnesota Department of Health, St. Paul, Minnesota;

3. Career Epidemiology Field Officer Program, Centers for Disease Control and Prevention, Atlanta, Georgia;

4. M Health Fairview Clinic, Brooklyn Park, Minnesota;

5. Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia;

6. Mounds View Animal Hospital, Mounds View, Minnesota

Abstract

ABSTRACT. Leptospirosis affects numerous animal species, including domestic dogs, but documented transmission to humans is rare. Here, we describe epidemiologically linked cases in a 12-year-old Minnesota boy and his pet dog. While human leptospirosis is often thought of as a disease of tropical locations, this case report describes a rare documented example of local transmission in the northern United States, a region historically not perceived to be at high risk of Leptospira species transmission to humans. This case highlights an unusual presentation, with facial nerve palsy, underappreciated epidemiological risks, and diagnostic challenges of this reemerging infection.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference23 articles.

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2. Evaluation of 3 serological tests for early detection of Leptospira-specific antibodies in experimentally infected dogs;Lizer,2018

3. Optimization of LipL32 PCR assay for increased sensitivity in diagnosing leptospirosis;Galloway,2015

4. Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene;Stoddard,2009

5. Direct detection and differentiation of pathogenic Leptospira species using a multi-gene targeted real time PCR approach;Ferreira,2014

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