Seroprevalence of Chagas Disease among People of Latin American Descent Living in Suffolk County, Long Island, New York

Author:

Saldivar Miguel A.1,Michelen Yamil E.1,Milla Lucia1,Kalogeropoulos Andreas P.2,Sin Eric1,Hellman Harriet L.3,Gilman Robert H.4,Marcos Luis A.15

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, Stony Brook University, Stony Brook, New York;

2. Division of Cardiology, Department of Internal Medicine, Stony Brook University, Stony Brook, New York;

3. Department of Pediatrics, Hampton Community Health Care, Southampton, New York;

4. Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland;

5. Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York

Abstract

ABSTRACT. This cross-sectional study estimated a one-time point seroprevalence rate of Chagas disease among people of Latin American descent in Suffolk County, Long Island, New York. Subjects who met the inclusion criteria were screened using the Chagas Detect Plus Rapid Test (InBios, Seattle, WA) with confirmation via Trypanosoma cruzi enzyme immunoassay and T. cruzi immunoblot assay. Administration of a questionnaire regarding demographics and risk factors followed. A seroprevalence rate of 10.74% was found. Identified risk factors included prior residence in a palm leaf house (odds ratio [OR], 10.42; P = 0.003; 95% CI, 2.18–49.76), residence in a house with triatomines (OR, 9.03; P = 0.006; 95% CI, 1.90–42.88), and history of triatomine bite (OR, 9.52; P = 0.009; 95% CI, 1.75–51.77). Our findings emphasize the importance of this frequently underdiagnosed disease and help highlight the importance of early screening among high-risk populations.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference19 articles.

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4. Chagas disease;Rassi,2010

5. Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association;Nunes,2018

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