Case Report: The Use of In Vivo Confocal Microscopy for Diagnosis and Monitoring in a Rare Case of Ancaliia algerae Microsporidial Keratitis in New South Wales, Australia

Author:

Sutton Kathryn M.1,Watts Matthew R.234,Athavale Daniel D.5,Lewis Noni6,Petsoglou Constantinos46,Hudson Bernard J.47,Fernando Suran L.14

Affiliation:

1. Department of Clinical Immunology and Allergy, Royal North Shore Hospital, Sydney, Australia;

2. Centre for Infectious Diseases and Microbiology Public Health, Westmead, Australia;

3. Institute for Clinical Pathology and Medical Research—New South Wales Health Pathology, Westmead, Australia;

4. University of Sydney, Sydney, Australia;

5. Department of Ophthalmology, Royal North Shore Hospital, Sydney, Australia;

6. Department of Ophthalmology, Sydney Eye Hospital, Sydney, Australia;

7. Department of Clinical Microbiology and Infectious Diseases, Royal North Shore Hospital, Sydney, Australia

Abstract

ABSTRACT. We describe the successful management of Ancaliia Algerae microsporidial keratitis in an immunosuppressed 54-year-old woman with refractory linear IgA disease. The case highlights the challenges in diagnosis and management of this infection in immunocompromised individuals and emphasizes the usefulness of in vivo confocal microscopy as a novel, noninvasive tool to aid in the diagnosis and monitoring of microsporidial keratitis. We also discuss the possible mode of acquisition of this rare infection.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference17 articles.

1. Microsporidiosis in humans;Han,2021

2. Anncaliia algerae microsporidial myositis;Watts,2014

3. Fatal disseminated Anncaliia algerae myositis mimicking polymyositis in an immunocompromised patient;Ziad,2021

4. Anncaliia algerae microsporidial myositis, New South Wales, Australia;Sutrave,2018

5. Successful treatment of disseminated Anncaliia algerae microsporidial infection with combination fumagillin and albendazole;Boileau,2016

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