Case Report: Relapsing Leptospirosis in an Immunocompromised Host-Reference-Cited by-同舟云学术

Case Report: Relapsing Leptospirosis in an Immunocompromised Host

Published:2023-10-04 Issue:4 Volume:109 Page:730-732
ISSN:0002-9637
Container-title:The American Journal of Tropical Medicine and Hygiene
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Author:

Prasad Ritika¹,Narsana Niyati K.²,Ajayi Antonette A.³,Wang Hannah⁴,Patel Jayna⁵,Ho Dora Y.¹,Banaei Niaz¹⁶,Blackburn Brian G.¹

Affiliation:

1. Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California;

2. Division of Infectious Diseases, Department of Internal Medicine, Davis School of Medicine, University of California, Sacramento, California;

3. Critical Care Medicine and Pulmonary Disease, Montage Health, Monterey, California;

4. Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio;

5. Division of Oncology, Department of Medicine, Stanford Health Care, Stanford, California;

6. Department of Pathology, Stanford University School of Medicine, Stanford, California

Abstract

ABSTRACT. Leptospirosis is typically a self-limited febrile illness; when it occurs, meningitis usually develops early in the course. Here, we describe a patient who had engaged in freshwater activities in Kauai that was immunocompromised due to a history of mantle cell lymphoma, autologous hematopoietic cell transplant, and hypogammaglobulinemia. He developed leptospiral meningoencephalitis 11 weeks after illness onset and persistently detectable Leptospira DNA in blood and cerebrospinal fluid along with ongoing clinical illness, despite appropriate treatment.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

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