Abstract
Herein, we report a dual biosensing platform operating viz., electrochemical and fluorescence mode for the cancer biomarker, CA15–3 detection. A one-step strategy was employed to synthesize sulphur doped graphitic carbon nitride nanosheets (S-g-C3N4). The presence of heteroatom (sulphur) in the molecular structure improved the optoelectronic properties and the surface functional group (–NH2) facilitated the covalent binding of antibodies and improved the selectivity during the analysis. The proposed biosensing platform was able to quantify very low concentration of the cancer biomarker, CA15–3 (2.9 U mL−1) in human serum samples and thereby evidenced the usefulness of this platform for clinical analysis and early disease diagnosis.
Funder
CSIR-Central ElectroChemical Research Institute
Publisher
The Electrochemical Society
Subject
Materials Chemistry,Electrochemistry,Surfaces, Coatings and Films,Condensed Matter Physics,Renewable Energy, Sustainability and the Environment,Electronic, Optical and Magnetic Materials
Cited by
16 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献