Abstract
A cold plasma system was used for Silver nanofilm coating of silk material. The Silver coated material was further modified by soaking in a 10−3 mol l−1 solution of α-cyclodextrin. The modified silk material was served as working electrode for simultaneous molecular recognition of specific biomarkers. CA19-9, CEA and p53 served as model analytes to prove that the disposable stochastic sensor can be used for simultaneous molecular recognition of specific biomarkers. The signatures (toff value) obtained for p53, CEA and CA19-9 were different, proving that the proposed disposable stochastic sensor is selective, and can be used for molecular recognition of these biomarkers in whole blood and tumoral tissue samples.
Funder
Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii
Publisher
The Electrochemical Society
Subject
Materials Chemistry,Electrochemistry,Surfaces, Coatings and Films,Condensed Matter Physics,Renewable Energy, Sustainability and the Environment,Electronic, Optical and Magnetic Materials
Cited by
7 articles.
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