Progress in the Study of Renal Injury Caused by a Novel Coronavirus

Author:

Lu Xian,Lei Genping,Yang Dong,Bai Jingxue

Abstract

Novel Corona Virus Pneumonia (Corona Virus Disease 2019, COVID-19) in December 2019 became an epidemic disease. Chronic kidney disease (CKD) patients are highly sensitive to COVID-19, in-depth study and understanding of the mechanism of action and prevention and treatment strategies of CKD patients infected with novel coronavirus appears to be crucial. This article explored the selected topic by combing the relevant literature, and summarized the susceptibility to COVID-19 and the mechanism of renal involvement in CKD patients; the article shows that COVID-19 mainly enters the cells with ACE2 as the receptor to damage the kidneys directly, but also through cytokine storm, endothelial damage, immune dysregulation and other indirect ways of renal damage.

Publisher

Century Science Publishing Co

Reference29 articles.

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