Adölesan Dönemde Polikistik Over Sendromu: Fiziksel, Metabolik ve Hormonal Özellikler

Abstract

Aim: The Rotterdam criteria are used in the diagnosis of polycystic ovary syndrome (PCOS). However, since menstrual irregularities and acne are seen more frequently in adolescents, it is theoretically difficult to use the Rotterdam criteria. The aim of this study was to investigate whether the Rotterdam criteria are sufficient for the diagnosis of PCOS in adolescence. Material and Methods: Thirty patients and thirty healthy individuals between the ages of 16 and 18 years were included in the study. Anthropometric measurements, Ferriman Gallwey score (FGS), ultrasonographic ovarian volumes, androgens, and other hormone levels of the participants were recorded. Results: There was a statistically significant positive correlation between the homeostatic model assessment of insulin resistance (HOMA-IR) and waist circumference/hip circumference ratio in the patient group (r=0.656, p<0.001). The mean luteinizing hormone (LH) levels of the patient group were found to be statistically significantly higher than the control group (p=0.048). The median FGS of the patient group was statistically significantly higher than the control group (p<0.001). Serum total testosterone levels of adolescent girls who have polycystic ovaries were statistically significantly higher than the ones who have not (p=0.001). The median FGS of those with polycystic ovarian appearance on ultrasonography was found to be statistically significantly higher than those without (p=0.034). Conclusion: Among the Rotterdam diagnostic criteria, oligoanovulation, acne, and polycystic ovarian appearance on ultrasonography can be seen in healthy adolescents without PCOS. In this study, the most supportive finding for the diagnosis of PCOS was the appearance of polycystic ovaries accompanying moderate hirsutism.