Analysis of the catalytic specificity of cytochrome P450 enzymes through site‐directed mutagenesis
Author:
Affiliation:
1. The Scripps Research InstituteDivision of BiochemistryLa JollaCalifornia92037USA
2. Goedecke AGDepartment of Drug MetabolismMooswaldallee 1‐97800FreiburgGermany
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fasebj.6.2.1537459
Cited by 38 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A single amino acid residue, Ala 105, confers 16α-hydroxylase activity to human cytochrome P450 17α-hydroxylase/17,20 lyase;The Journal of Steroid Biochemistry and Molecular Biology;2010-04
2. High-throughput enzymology and combinatorial mutagenesis for mining cytochrome P450 functions;Expert Opinion on Drug Metabolism & Toxicology;2008-06
3. Evidence for the functional role of residues in the B′–C loop of baboon cytochrome P450 side-chain cleavage (CYP11A1) obtained by site-directed mutagenesis, kinetic analysis and homology modelling;The Journal of Steroid Biochemistry and Molecular Biology;2007-01
4. Heterologous Expression of Mammalian P450 Enzymes;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22
5. P450 Active Site Architecture and Reversibility: Inactivation of Cytochromes P450 2B4 and 2B4 T302A by tert-Butyl Acetylenes;Biochemistry;2005-02-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3