Liver‐specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation

Author:

TORRES LUIS1,ÁVILA MATíAS A.1,CARRETERO M. VICTORIA1,LATASA M. UJUE1,CABALLERíA JOAN2,LóPEZ‐RODAS GERARDO3,BOUKABA ABDELHALIM3,LU SHELLY C.4,FRANCO LUIS3,MATO JOSé M.1

Affiliation:

1. Divisiãn de Hepatología y Terapia GénicaDepartamento de Medicina InternaFacultad de MedicinaUniversidad de Navarra 31008 Pamplona Spain

2. Servicio de HepatologíaHospital Clínico y Provincial 08036 Barcelona Spain

3. Departamento de Bioquímica y Biología MolecularUniversidad de Valencia Burjassot 46100 València Spain

4. Center for Liver Disease Research and Division of Gastrointestinal Liver DiseasesDepartment of MedicineUniversity of Southern California School of Medicine Los Angeles California 90033 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference35 articles.

1. Activation of methionine for transmethylation. III. The methionine‐activating enzyme of Baker's yeast;Mudd S. H.;J. Biol. Chem.,1958

2. S-adenosylmethionine synthesis: Molecular mechanisms and clinical implications

3. Differential expression pattern ofS-adenosylmethionine synthetase isoenzymes during rat liver development

4. Changes in S-adenosylmethionine synthetase in human liver cancer: Molecular characterization and significance

5. Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells;Cai J.;Cancer Res.,1998

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