Taurine treatment prevents derangement of the hepatic γ‐glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism

Author:

Maclean Kenneth N.1,Jiang Hua1,Aivazidis Stefanos2,Kim Eugene1,Shearn Colin T.2,Harris Peter S.2,Petersen Dennis R.2,Allen Robert H.3,Stabler Sally P.3,Roede James R.2

Affiliation:

1. Department of Pediatrics Aurora Colorado USA

2. Department of Pharmaceutical Sciences Aurora Colorado USA

3. Department of Medicine University of Colorado Health Sciences Center Aurora Colorado USA

Funder

Skaggs School of Pharmacy and Pharmaceutical Sciences

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference95 articles.

1. The natural history of homocystinuria due to cystathionine β‐synthase deficiency;Mudd S. H.;Am. J. Hum. Genet.,1985

2. Glutathione metabolism and its selective modification;Meister A.;J. Biol. Chem.,1988

3. [5] Diversity of glutathione peroxidases

4. Glutathione synthesis

5. Glyoxalase I – structure, function and a critical role in the enzymatic defence against glycation

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