FFAR2‐FFAR3 receptor heteromerization modulates short‐chain fatty acid sensing
Author:
Affiliation:
1. Department of Biological Sciences, Faculty of ScienceNational University of Singapore Singapore
2. Centre for Bioimaging SciencesNational University of Singapore Singapore
3. Mechanobiology InstituteNational University of Singapore Singapore
Funder
Taiho Pharmaceutical
National Medical Research Council
Ministry of Education
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201700252RR
Reference58 articles.
1. The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids
2. Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
3. Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
4. Activation of G Protein-Coupled Receptor 43 in Adipocytes Leads to Inhibition of Lipolysis and Suppression of Plasma Free Fatty Acids
5. Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet
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