Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans

Author:

Guillet Christelle1,Prod'homme Magali2,Balage Michèle2,Gachon Pierre1,Giraudet Christophe1,Morin Liliane1,Grizard Jean2,Boirie Yves1

Affiliation:

1. Unité du Métabolisme Protéino‐Energétique UMR Université d'Auvergne/INRA CRNH Centre Hospitalier Universitaire Clermont‐Ferrand France

2. Unité de Nutrition et du Métabolisme Protéique, INRA‐Theix CRNH Clermont‐Ferrand France

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference43 articles.

1. Sarcopenia: a major modifiable cause of frailty in the elderly;Roubenoff R.;J. Nutr. Health Aging,2000

2. Strength is a major factor in balance, gait, and the occurrence of falls;Wolfson L.;J. Gerontol. A Biol. Sci. Med. Sci.,1995

3. Myofibrillar protein synthesis in young and old men

4. Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78–84 and 23–32 yr olds

5. Muscle protein turnover: methodological issues and the effect of aging;Nair K. S.;J. Gerontol. A Biol. Sci. Med. Sci.,1995

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