Physiological loading of joints prevents cartilage degradation through CITED2

Author:

Leong Daniel J.12,Li Yong H.1,Gu Xiang I.2,Sun Li3,Zhou Zuping1,Nasser Philip1,Laudier Damien M.1,Iqbal Jameel3,Majeska Robert J.2,Schaffler Mitchell B.2,Goldring Mary B.4,Cardoso Luis2,Zaidi Mone3,Sun Hui B.1

Affiliation:

1. Leni and Peter W. May Department of OrthopedicsMount Sinai School of MedicineNew YorkNew YorkUSA

2. Department of Biomedical EngineeringCity College of New YorkNew YorkNew YorkUSA

3. Mount Sinai Bone ProgramMount Sinai School of MedicineNew YorkNew YorkUSA

4. Hospital for Special SurgeryNew YorkNew YorkUSA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference46 articles.

1. Perspectives on chondrocyte mechanobiology and osteoarthritis;Buckwalter J. A.;Biorheology,2006

2. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I

3. Softening of canine articular cartilage after immobilization of the knee joint;Jurvelin J.;Clin. Orthop. Relat. Res.,1986

4. Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement

5. Cartilage homeostasis in health and rheumatic diseases

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