Administration of granulocyte colony‐stimulating factor induces immunomodulation, recruitment of T regulatory cells, reduction of myocarditis and decrease of parasite load in a mouse model of chronic Chagas disease cardiomyopathy

Author:

Vasconcelos Juliana F.12,Souza Bruno S. F.12,Lins Thayse F. S.1,Garcia Letícia M. S.2,Kaneto Carla M.23,Sampaio Geraldo P.2,Alcântara Adriano C.2,Meira Cássio S.1,Macambira Simone G.124,Ribeiro‐dos‐Santos Ricardo2,Soares Milena B. P.12

Affiliation:

1. Centro de Pesquisas Gonçalo MonizFundação Oswaldo CruzSalvadorBahiaBrazil

2. Centro de Biotecnologia e Terapia CelularHospital São RafaelSalvadorBahiaBrazil

3. Universidade Estadual de Santa CruzIlhéusBahiaBrazil

4. Universidade Federal da BahiaSalvadorBahiaBrazil

Funder

Ministério da Ciência e Tecnologia

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Financiadora de Estudos e Projetos

Fundação Oswaldo Cruz

Fundação de Amparo à Pesquisa do Estado da Bahia

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference55 articles.

1. Chagas disease: an impediment in achieving the millennium development goals in Latin America;Franco‐Paredes C.;BMC Int. Health Hum. Rights,2007

2. The neglected tropical diseases of Latin America and the Caribbean: estimated disease burden and distribution and a roadmap for control and elimination;Hotez P. J.;PLoS Negl. Trop. Dis.,2008

3. The unfinished public health agenda of Chagas disease in the era of globalization;Franco‐Paredes C.;PLoS Negl. Trop. Dis.,2009

4. World Health Organization.Chagas disease. Retrieved November 1 2012 fromhttp://www.who.int/mediacentre/factsheets/fs340/en/index.html

5. Heart transplantation for chronic chagas' heart disease

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