Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction-Reference-Cited by-同舟云学术

Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction

Published:2020-04-23 Issue:6 Volume:34 Page:8139-8154
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Ghosh Rhia¹,Wood‐Kaczmar Alison¹,Dobson Lucianne¹,Smith Edward J.¹,Sirinathsinghji Eva C.¹,Kriston‐Vizi Janos²,Hargreaves Iain P.³,Heaton Robert³,Herrmann Frank⁴,Abramov Andrey Y.⁵,Lam Amanda J.⁶,Heales Simon J.⁶,Ketteler Robin²,Bates Gillian P.¹,Andre Ralph¹,Tabrizi Sarah J.¹

Affiliation:

1. Huntington's Disease Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology University College London London UK

2. MRC Laboratory for Molecular Cell Biology University College London London UK

3. School of Pharmacy Liverpool John Moores University Liverpool UK

4. Evotec AG Hamburg Germany

5. Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology University College London London UK

6. Neurometabolic Unit National Hospital for Neurology and Neurosurgery London UK

Funder

Takeda Pharmaceutical Company

Medical Research Council

Publisher

Wiley