A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway

Author:

Cui Di12,Drake Joshua C.1,Wilson Rebecca J.13,Shute Robert J.1,Lewellen Bevan1,Zhang Mei14,Zhao Henan1,Sabik Olivia L.35,Onengut Suna5,Berr Stuart S.6,Rich Stephen S.5,Farber Charles R.357,Yan Zhen1489

Affiliation:

1. Center for Skeletal Muscle Research at Robert M. Berne Cardiovascular Research Center University of Virginia School of Medicine Charlottesville VA USA

2. Key Laboratory of Adolescent and Exercise Intervention, Ministry of Education East China Normal University Shanghai China

3. Department of Biochemistry and Molecular Genetics University of Virginia School of Medicine Charlottesville VA USA

4. Departments of Medicine University of Virginia School of Medicine Charlottesville VA USA

5. Center for Public Health Genomics University of Virginia School of Medicine Charlottesville VA USA

6. Department of Radiology and Medical Imaging University of Virginia School of Medicine Charlottesville VA USA

7. Department of Public Health Sciences University of Virginia School of Medicine Charlottesville VA USA

8. Department of Pharmacology University of Virginia School of Medicine Charlottesville VA USA

9. Department of Molecular Physiology and Biological Physics University of Virginia School of Medicine Charlottesville VA USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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