Assessing the efficacy of antiparasitic sprays

Author:

Paliy A. P.1ORCID,Sumakova N. V.1ORCID,Bohach O. M.1ORCID,Bogach M. V.1ORCID,Pavlichenko O. V.2ORCID,Ihnatieva T. M.2ORCID,Dubin R. A.3ORCID

Affiliation:

1. National Scientific Center “Institute of Experimental and Clinical Veterinary Medicine”, Kharkiv, Ukraine

2. State Biotechnological University

3. Odesa State Agrarian University

Abstract

For the control of animal ectoparasites, a large number of prophylactic and therapeutic agents with different active ingredients and routes of administration have been proposed. The persistence of ectoparasitic infections in domestic animals has led to the search for more effective drugs and innovative forms of their production. The aim of the study was to establish and experimentally confirm the efficacy of innovative ectoparasiticidal sprays for dogs and cats for prophylactic and therapeutic purposes in parasitic infections. The antiparasitic agents used in the experiments were ‘PROFILINE Spray’, ‘INSECTOSTOP Spray’, and ‘Barrier-Super Insecticidal Spray’. In accordance with the tasks set, the research was carried out using visual and microscopic methods in accordance with existing practical guidelines and current methodological recommendations. In the study of ectoparasite collections, ixodid ticks (Ixodes ricinus), dog fleas (Ctenocephalus canis), and cat fleas (Ctenocephalus felis) were found. It was shown that the knockdown effect in all ticks began with a state of disorientation, the ticks began to move chaotically 6 hours after exposure to the experimental agents, and after 12 hours there was a complete knockdown of all experimental ixodid ticks and fleas. The high efficacy of ‘PROFILINE Spray’, ‘INSECTOSTOP Spray’, and ‘Barrier-Super Insecticidal Spray’ against fleas (Ctenocephalides spp.), lice (Trichodectes canis, Felicola subrostratus), lice (Linognathus setosus), and ixodid ticks (Ixodes spp.) was experimentally proven. The efficacy of the products is 100% within 60 days of application to animals. According to the results of the studies, it was found that the investigated veterinary sprays can be used for the prevention and treatment of pets with fleas, lice, and ixodid ticks

Publisher

Kharkiv Entomological Society

Subject

General Medicine

Reference23 articles.

1. CE (The Council of Europe). (1986) European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes. (European Treaty Series, No. 123). Strasbourg: The Council of Europe. Available at: https://conventions.coe.int/treaty/en/treaties/html/123.htm.

2. CEC (The Council of the European Communities) (2010) ‘Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes’, The Official Journal of the European Communities, L 276, pp. 33–79. Available at: http://data.europa.eu/eli/dir/2010/63/oj.

3. Cvejić, D., Schneider, C., Neethling, W., Hellmann, K., Liebenberg, J. and Navarro, C. (2017) ‘The sustained speed of kill of ticks (Rhipicephalus sanguineus) and fleas (Ctenocephalides felis felis) on dogs by a spot-on combination of fipronil and permethrin (Effitix®) compared with oral afoxolaner (NexGard®)’, Veterinary Parasitology, 243, pp. 52–57. doi: 10.1016/j.vetpar.2017.06.011.

4. Diaz, S. L. (2005) ‘Efficacy of fipronil in the treatment of pediculosis in laboratory rats’, Laboratory Animals, 39(3), pp. 331–335. doi: 10.1258/0023677054306980.

5. EMA (European Medicines Agency) (2023) Reflection Paper on Resistance in Ectoparasites. EMA/CVMP/EWP/310225/2014. Amsterdam, The Netherland: European Medicines Agency. Available at: https://www.ema.europa.eu/en/reflection-paper-resistance-ectoparasites-scientific-guideline.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Effectiveness of modern antiparasitic animal collars;Journal for Veterinary Medicine, Biotechnology and Biosafety;2024-03-28

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3