Synthesis, Characterization and Antibacterial Activity of Schiff Base Hybrid from 2-Aminothiazole-pyrazolecarboxaldehyde

Author:

Rameshwar M.1,Archana B.1,Sachin P.1,Vivek T.2ORCID,Subhash B.1

Affiliation:

1. P.G. Department of Chemistry, Yeshwant Mahavidyalala, Nanded – 431 602, Maharashtra, India.

2. Department of Chemistry, Shri R.R. Lahoti Science College, Morshi – 444 905, Maharashtra, India.

Abstract

The five Schiff bases hybrid have been synthesized from 2-aminothiazole and pyrazole-4-carboxaldehyde under basic condition. The structure of novel compounds were established on the basis of their elemental analyses IR, 1H NMR and 13C NMR, and then screened for their in vitro antimicrobial activity. Among them 3b and 3d showed excellent activity when compared to other derivatives. Other remaining derivatives showed moderate activity.

Publisher

JACS Directory

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