Measured Neutralizing Titers of IFN-β Neutralizing Antibodies (NAbs) Can Depend on the Preparations of IFN-β Used in the Assay
Author:
Affiliation:
1. J. Files Consulting, San Rafael, CA 94901.
2. Esoterix Clinical Trial Services, a LabCorp Company, San Leandro, CA 94577.
3. Wellness Managements, Morristown Memorial Hospital, Morristown, NJ 07960.
Publisher
Mary Ann Liebert Inc
Subject
Virology,Cell Biology,Immunology
Link
http://www.liebertpub.com/doi/pdf/10.1089/jir.2006.0131
Reference23 articles.
1. Immunogenicity of recombinant human proteins: causes and consequences
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5. Disease modifying therapies in multiple sclerosis: Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines: Table 1.
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2. Use of a Standardized MxA Protein Measurement-Based Assay for Validation of Assays for the Assessment of Neutralizing Antibodies Against Interferon-β;Journal of Interferon & Cytokine Research;2013-11
3. Development and characterization of a non-cell-based assay to assess the presence of neutralizing antibodies to interferon-beta in clinical samples;Journal of Immunological Methods;2013-09
4. Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies;Journal of Neuroinflammation;2012-06-15
5. Standardization of Neutralizing Antibody Unitage by Bioassay Design: Constant Antigen and Constant Antibody Methodology;Detection and Quantification of Antibodies to Biopharmaceuticals;2011-06-20
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