Antigen-Specific Immunotherapy with Thyrotropin Receptor Peptides in Graves' Hyperthyroidism: A Phase I Study

Author:

Pearce Simon H.S.1,Dayan Colin2,Wraith David C.345,Barrell Kevin5,Olive Natalie5,Jansson Lotta6,Walker-Smith Terrie5,Carnegie Christina5,Martin Keith F.5,Boelaert Kristien4,Gilbert Jackie7,Higham Claire E.8,Muller Ilaria2,Murray Robert D.9,Perros Petros10,Razvi Salman11,Vaidya Bijay12,Wernig Florian13,Kahaly George J.14

Affiliation:

1. Institute for Genetic Medicine, Newcastle University, and Newcastle Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

2. Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom.

3. Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham United Kingdom.

4. Institute of Metabolism and Systems Research, University of Birmingham, Birmingham United Kingdom.

5. Apitope Technology (Bristol) Ltd., Chepstow, United Kingdom.

6. Apitope International NV, Diepenbeek, Belgium.

7. Department of Endocrinology, King's College Hospital, London, United Kingdom.

8. Department of Endocrinology, Christie Hospital NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

9. Department of Endocrinology, St. James's University Hospital, Leeds, United Kingdom.

10. Endocrine Unit, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

11. Institute for Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

12. Macleod Diabetes & Endocrine Centre, Royal Devon and Exeter Hospital, Exeter, United Kingdom.

13. Department of Endocrinology, Imperial College, London, United Kingdom.

14. Department of Medicine I, Johannes Gutenberg University Medical Center, Mainz, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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1. Strategies and delivery systems for cell-based therapy in autoimmunity;Frontiers in Drug Delivery;2024-08-08

2. Graves disease: latest understanding of pathogenesis and treatment options;Nature Reviews Endocrinology;2024-07-22

3. Prospects for targeted therapy of Graves' disease: A review;Consilium Medicum;2024-05-20

4. Le terapie a bersaglio molecolare nel trattamento del morbo di Basedow;L'Endocrinologo;2024-03-06

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