Tocilizumab-Induced Unexpected Increase of Several Inflammatory Cytokines in Critically Ill COVID-19 Patients: The Anti-Inflammatory Side of IL-6

Author:

Ponthieux Fanny1ORCID,Dauby Nicolas23,Maillart Evelyne4,Fils Jean-François5,Smet Julie1,Claus Marc6,Besse-Hammer Tatiana7,Bels David De8,Corazza Francis19,Nagant Carole1

Affiliation:

1. Immunology Department, LHUB-ULB, Université libre de Bruxelles (ULB), Brussels, Belgium.

2. Department of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université libre de Bruxelles (ULB), Brussels, Belgium.

3. Institute for Medical Immunology, Université libre de Bruxelles (ULB), Brussels, Belgium.

4. Department of Infectious Disease, Brugmann University Hospital, Brussels, Belgium.

5. Ars Statistica, Brussels, Belgium.

6. Department of Intensive Care, Centre Hospitalier Universitaire Saint-Pierre, Université libre de Bruxelles (ULB), Brussels, Belgium.

7. Clinical Research Department, Brugmann University Hospital, Brussels, Belgium.

8. Department of Intensive Care, Brugmann University Hospital, Brussels, Belgium.

9. Laboratory of Translational Research, Brugmann University Hospital, Université libre de Bruxelles (ULB), Brussels, Belgium.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Molecular Medicine,Immunology

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