Targeted Inhibition of PAI-1 Activity Impairs Epithelial Migration and Wound Closure Following Cutaneous Injury
Author:
Affiliation:
1. Center for Cell Biology and Cancer Research, Albany Medical College, Albany, New York.
2. Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida.
Publisher
Mary Ann Liebert Inc
Subject
Critical Care and Intensive Care Medicine,Emergency Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/wound.2014.0611
Reference36 articles.
1. PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair
2. SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair
3. PAI-1 gene expression is regionally induced in wounded epithelial cell monolayers and required for injury repair
4. The Transcriptional Program in the Response of Human Fibroblasts to Serum
5. PAI-1 transcriptional regulation during the G0 → G1 transition in human epidermal keratinocytes
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