Role of Endogenous IFN-γ in Macrophage Programming Induced by IL-12 and IL-18
Author:
Affiliation:
1. Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Publisher
Mary Ann Liebert Inc
Subject
Virology,Cell Biology,Immunology
Link
http://www.liebertpub.com/doi/pdf/10.1089/jir.2007.0128
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1. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.
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3. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.
4. The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge
5. Interleukin-12 profoundly up-regulates the synthesis of antigen-specific complement-fixing IgG2a, IgG2b and IgG3 antibody subclassesin vivo
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