Development of an Assay for Complex I/Complex III of the Respiratory Chain Using Solid Supported Membranes and Its Application in Mitochondrial Toxicity Screening in Drug Discovery-Reference-Cited by-同舟云学术

Development of an Assay for Complex I/Complex III of the Respiratory Chain Using Solid Supported Membranes and Its Application in Mitochondrial Toxicity Screening in Drug Discovery

Published:2011-04 Issue:2 Volume:9 Page:147-156
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Preißl Sebastian¹²,Bick Inga³,Obrdlik Petr³,Diekert Kerstin³,Gul Sheraz¹,Gribbon Philip¹

Affiliation:

1. European ScreeningPort GmbH, Hamburg, Germany.

2. Institute of Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg, Freiburg, Germany.

3. IonGate Biosciences GmbH, Frankfurt/Main, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2010.0320

Reference45 articles.

1. A century of mitochondrial research: achievements and perspectives

2. Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays

3. A Subtype of Diabetes Mellitus Associated with a Mutation of Mitochondrial DNA

4. Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reconstitution of Respiratory Complex I on a Biomimetic Membrane Supported on Gold Electrodes;Langmuir;2014-07-16

2. Measuring Interference of Drug-Like Molecules with the Respiratory Chain: Toward the Early Identification of Mitochondrial Uncouplers in Lead Finding;ASSAY and Drug Development Technologies;2013-09