Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model-Reference-Cited by-同舟云学术

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model

Published:2016-04-10 Issue:11 Volume:24 Page:575-589
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Zhang Jingwen¹,Ahn Kwang Seok²,Kim Chulwon²,Shanmugam Muthu K.¹,Siveen Kodappully Sivaraman¹,Arfuso Frank³,Samym Ramar Perumal⁴⁵⁶,Deivasigamanim Amudha⁷,Lim Lina Hsiu Kim⁶,Wang Lingzhi¹⁸,Goh Boon Cher¹⁸,Kumar Alan Prem¹⁸⁹¹⁰,Hui Kam Man⁷,Sethi Gautam¹⁹

Affiliation:

1. Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

2. College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

3. School of Biomedical Sciences, CHIRI Biosciences Research Precinct, Curtin University, Perth, Australia.

4. Department of Anatomy, Venom and Toxin Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

5. Department of Microbiology Infectious Diseases Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

6. Department of Physiology, NUS Immunology Programme, Centre for Life Sciences, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

7. Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore.

8. Centre for Translational Medicine (CeTM), Cancer Science Institute, National University of Singapore, Singapore, Singapore.

9. School of Biomedical Sciences, Curtin University, Perth, Australia.

10. Department of Biological Sciences, University of North Texas, Denton, Texas.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2015.6418

Reference49 articles.

1. IL-6 signaling by STAT3 participates in the change from hyperplasia to neoplasia in NRP-152 and NRP-154 rat prostatic epithelial cells

2. Oncogenic kinase signalling

3. Chemopreventive and therapeutic effects of nimbolide in cancer: The underlying mechanisms

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