Targeting the Glycoprotein 130 Receptor Subunit to Control Pain and Inflammation-Reference-Cited by-同舟云学术

Targeting the Glycoprotein 130 Receptor Subunit to Control Pain and Inflammation

Published:2010-12 Issue:12 Volume:30 Page:865-873
ISSN:1079-9907
Container-title:Journal of Interferon & Cytokine Research
language:en
Short-container-title:Journal of Interferon & Cytokine Research

Author:

Jazayeri Jalal A.¹,Upadhyay Aradhana¹,Vernallis Ann B.²,Carroll Graeme J.³

Affiliation:

1. Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), Melbourne, Australia.

2. School of Life and Health Sciences, Aston University Birmingham, Birmingham, United Kingdom.

3. Department of Rheumatology, Fremantle Hospital, University of Notre Dame, Australia (Fremantle) and University of Western Australia, Fremantle Hospital, Perth, Western Australia.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Cell Biology,Immunology

Link

http://www.liebertpub.com/doi/pdf/10.1089/jir.2010.0035

Reference52 articles.

1. A Fusion Protein of the gp130 and Interleukin-6Rα Ligand-binding Domains Acts as a Potent Interleukin-6 Inhibitor

2. A Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

3. Role of the intracellular receptor domain of gp130 (exon 17) in human inflammatory bowel disease

4. Blocking signaling through the gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity

5. A phase I, pharmacokinetic (PK), and preliminary efficacy assessment of ALD518, a humanized anti-IL-6 antibody, in patients with advanced cancer

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