Development of a Cell-Based Fluorescence Polarization Biosensor Using Preproinsulin to Identify Compounds That Alter Insulin Granule Dynamics-Reference-Cited by-同舟云学术

Development of a Cell-Based Fluorescence Polarization Biosensor Using Preproinsulin to Identify Compounds That Alter Insulin Granule Dynamics

Published:2015-11 Issue:9 Volume:13 Page:558-569
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Yi Na Young¹,He Qingping¹,Caligan Thomas B.¹,Smith Ginger R.¹,Forsberg Lawrence J.²,Brenman Jay E.²,Sexton Jonathan Z.¹

Affiliation:

1. Biomanufacturing Research Institute and Technology Enterprise, Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina.

2. The Neuroscience Center and Department of Cell Biology & Physiology, UNC Chapel Hill School of Medicine, Chapel Hill, North Carolina.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2015.665

Reference23 articles.

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2. High Expression Rates of Human Islet Amyloid Polypeptide Induce Endoplasmic Reticulum Stress–Mediated β-Cell Apoptosis, a Characteristic of Humans With Type 2 but Not Type 1 Diabetes

3. Executive Summary: Standards of Medical Care in Diabetes—2010

4. Unraveling the Science of Incretin Biology

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