Protective Immunity Against Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain After Vaccination with Genes Encoding the Amastigote Surface Protein-2 and Trans-Sialidase-Reference-Cited by-同舟云学术

Protective Immunity Against Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain After Vaccination with Genes Encoding the Amastigote Surface Protein-2 and Trans-Sialidase

Published:2004-09 Issue:9 Volume:15 Page:878-886
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Vasconcelos José Ronnie¹,Hiyane Meire I.¹,Marinho Cláudio R.F.²,Claser Carla¹,Machado Alexandre M.V.³,Gazzinelli Ricardo T.³,Bruña-Romero Oscar³,Alvarez José M.²,Boscardin Silvia B.⁴,Rodrigues Mauricio M.¹

Affiliation:

1. Centro Interdisciplinar de Terapia Gênica (CINTERGEN), Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo-Escola Paulista de Medicina, São Paulo, SP, Brazil, 04044-010.

2. Departamento de Imunologia, ICB, Universidade de São Paulo, São Paulo, SP, Brazil, 05508-900.

3. Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais e Centro de Pesquisas René Rachou, FIOCRUZ, Barro Preto, Belo Horizonte, Minas Gerais, Brazil, 30190-002.

4. Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo-Escola Paulista de Medicina, São Paulo, SP, Brazil, 04044-010.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2004.15.878

Reference22 articles.

1. Immunization with cDNA Expressed by Amastigotes of Trypanosoma cruzi Elicits Protective Immune Response against Experimental Infection

2. Immunization with a plasmid DNA containing the gene of trans-sialidase reduces Trypanosoma cruzi infection in mice

3. Immunotherapy of Trypanosoma cruzi Infection with DNA Vaccines in Mice

4. Genetic immunization with LYT1 or a pool of trans-sialidase genes protects mice from lethal Trypanosoma cruzi infection

5. DNA Sequences Encoding CD4 + and CD8 + T-Cell Epitopes Are Important for Efficient Protective Immunity Induced by DNA Vaccination with a Trypanosoma cruzi Gene

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