<i>In Vitro</i> CRISPR-Cas12a-Based Detection of Cancer-Associated <i>TP53</i> Hotspot Mutations Beyond the crRNA Seed Region-Reference-Cited by-同舟云学术

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In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region

Published:2023-04-01 Issue:2 Volume:6 Page:127-139
ISSN:2573-1599
Container-title:The CRISPR Journal
language:en
Short-container-title:The CRISPR Journal

Author:

Kohabir Kavish A.V.¹²³^ORCID,Nooi Lars O.¹,Brink Arjen⁴⁵,Brakenhoff Ruud H.³⁴⁵,Sistermans Erik A.¹²,Wolthuis Rob M.F.¹⁴

Affiliation:

1. Department of Human Genetics, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

2. Embryonic & Fetal Development, Amsterdam Reproduction & Development, Amsterdam, The Netherlands.

3. Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, The Netherlands.

4. Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, The Netherlands.

5. Department of Otolaryngology/Head and Neck Surgery, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Biotechnology

Link

https://www.liebertpub.com/doi/pdf/10.1089/crispr.2022.0077

Reference46 articles.

1. Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review

2. Liquid biopsies come of age: towards implementation of circulating tumour DNA

3. Why are there hotspot mutations in the TP53 gene in human cancers?

4. The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute

5. The CRISPR tool kit for genome editing and beyond

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CRISPR for companion diagnostics in low-resource settings;Lab on a Chip;2024

2. New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity;Nucleic Acids Research;2023-11-30

3. New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity;2023-07-28

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