Overcoming the Innate Immune Response to Small Interfering RNA
Author:
Affiliation:
1. Protiva Biotherapeutics, Burnaby, British Columbia, Canada V5G 4Y1.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2007.179
Reference102 articles.
1. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2. Fully 2‘-Modified Oligonucleotide Duplexes with Improved in Vitro Potency and Stability Compared to Unmodified Small Interfering RNA
3. Progress towards in Vivo Use of siRNAs
4. Plasmacytoid Dendritic Cells Control TLR7 Sensitivity of Naive B Cells via Type I IFN
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