Comparison of Adeno-Associated Viral Vector Serotypes for Spinal Cord and Motor Neuron Gene Delivery
Author:
Affiliation:
1. Department of Neurosurgery, Emory University, Atlanta, GA 30322.
2. Center for Gene Therapy, University of North Carolina, Chapel Hill, NC 27599.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2011.008
Reference21 articles.
1. Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System
2. Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons
3. Cerebrospinal Fluid and Spinal Cord Distribution of Hyperbaric Bupivacaine and Baclofen during Slow Intrathecal Infusion in Pigs
4. Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
5. Production and characterization of adeno-associated viral vectors
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