Do CARs Need a Driver's License? Adoptive Cell Therapy with Chimeric Antigen Receptor-Redirected T Cells Has Caused Serious Adverse Events-Reference-Cited by-同舟云学术

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Do CARs Need a Driver's License? Adoptive Cell Therapy with Chimeric Antigen Receptor-Redirected T Cells Has Caused Serious Adverse Events

Published:2010-09 Issue:9 Volume:21 Page:1039-1042
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Büning Hildegard¹,Uckert Wolfgang²,Cichutek Klaus³,Hawkins Robert E.⁴,Abken Hinrich¹

Affiliation:

1. Zentrum für Molekulare Medizin Köln and Klinik I für Innere Medizin, Uniklinik Köln, D-50937 Cologne, Germany.

2. Max-Delbrück-Centrum für Molekulare Medizin, D-13125 Berlin-Buch, Germany.

3. Paul Ehrlich Institut, D-63225 Langen, Germany.

4. Department of Medical Oncology, Paterson Institute of Cancer Research, University of Manchester, Manchester, M20 4BX, UK.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2010.131

Reference25 articles.

1. Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer

2. Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial

3. Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts

4. Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

5. T Cell Activation by Antibody-Like Immunoreceptors: Increase in Affinity of the Single-Chain Fragment Domain above Threshold Does Not Increase T Cell Activation against Antigen-Positive Target Cells but Decreases Selectivity

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1. CAR‐T cell therapy;Molecular Hematology;2024-03-08

2. In Vitro Engineering Chimeric Antigen Receptor Macrophages and T Cells by Lipid Nanoparticle-Mediated mRNA Delivery;ACS Biomaterials Science & Engineering;2022-02-01

3. Recent advances in tumor associated carbohydrate antigen based chimeric antigen receptor T cells and bispecific antibodies for anti-cancer immunotherapy;Seminars in Immunology;2020-02

4. Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering;Nano Letters;2020-01-17

5. Current Perspectives in Cancer Immunotherapy;Cancers;2019-09-30

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