A Novel Class of Immune-Stimulatory CpG Oligodeoxynucleotides Unifies High Potency in Type I Interferon Induction with Preferred Structural Properties-Reference-Cited by-同舟云学术

A Novel Class of Immune-Stimulatory CpG Oligodeoxynucleotides Unifies High Potency in Type I Interferon Induction with Preferred Structural Properties

Published:2010-04 Issue:2 Volume:20 Page:93-101
ISSN:1545-4576
Container-title:Oligonucleotides
language:en
Short-container-title:Oligonucleotides

Author:

Samulowitz Ulrike¹,Weber Markus¹,Weeratna Risini²,Uhlmann Eugen¹,Noll Bernhard¹,Krieg Arthur M.³,Vollmer Jörg¹

Affiliation:

1. Coley Pharmaceutical GmbH—A Pfizer Company, Düsseldorf, Germany.

2. Pfizer Vaccines Research, Ottawa, Ontario, Canada.

3. Pfizer Inc., Research Technology Center, Cambridge, Massachusetts.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/oli.2009.0210

Reference36 articles.

1. Deoxycytidyl-Deoxyguanosine Oligonucleotide Classes A, B, and C Induce Distinct Cytokine Gene Expression Patterns in Rhesus Monkey Peripheral Blood Mononuclear Cells and Distinct Alpha Interferon Responses in TLR9-Expressing Rhesus Monkey Plasmacytoid Dendritic Cells

2. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

3. Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers

4. Structural studies of oligonucleotides containing G-quadruplex motifs using AFM

5. Differential Effects of P-Class Versus Other CpG Oligodeoxynucleotide Classes on the Impaired Innate Immunity of Plasmacytoid Dendritic Cells in HIV Type 1 Infection

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