Investigation of Antibacterial Effect of Bupleurum lancifolium Hornem.

Abstract

Humanbeing was widely used several medicinal plants for the purpose of protection from illness and treatment of diseases from past to present time. Nowadays, antibiotics are often used against infections. Thus, microorganisms have been resistance against antibiotics. As a result, the antibiotic resistancy is become an important health problem. So as to solve the problem that related to antibiotics resistancy, medicinal plants which is studied regarding medicinal properties, is a most effective way for solution. We need that determine the antimicrobial activities of active substance obtained by different methods from various parts of plants such as roots, steems, leaves, flowers, fruits and seeds. In this study, extracts were prepared from root and aerial parts of Bupleurum lancifolium by using two different methods with various solvents. These extracts tested against 14 Gram-positive and Gram-negative bacterial strains by microdilution method. As a result, in the concentration range from 80 µg ml-1 to 0.15625 µg ml-1, the extracts of Bupleurum lancifolium did not have antibacterial effect against test bacteria.