Investigation of Magnetic Gradient Distribution Usability Generated by Helmholtz Coils for Magnetic Hyperthermia Localization

Abstract

Magnetic fluid hyperthermia (MFH) is new generation cancer treatment method. One of the challenges that arise in practical applications of MFH tests is limited control of MNP (magnetic nano particle) vibrations. Localization of vibrations can be achieved through static gradients. In this study, static gradient patterns that can be used in new generation MFH tests were created with Helmholtz coils. Finite element simulation method is used to predict magnetic field pattern that will occur in work area. A platform has been produced where coils can be placed along an axis and their currents can be changed. It is made possible to dynamically change the localizing SMF gradient and field-free region (FFR) size by changing source currents. Arduino based magnetic field measurement system is simulated in a circuit simulation program and designed. Inferences made comparatively present the usability of magnetic field patterns obtained by current changes for new generation MFH approach. In addition, the proposed electronic measurement design can be adopted to determine gradient distribution at low cost without the need for expensive measurement systems.