Current understanding of the aetiology and pathogenesis of inflammatory bowel diseases (Part 2): the role of the microbiome and nutritional factors-Reference-Cited by-同舟云学术

Current understanding of the aetiology and pathogenesis of inflammatory bowel diseases (Part 2): the role of the microbiome and nutritional factors

Published:2023-12-18 Issue:12 Volume: Page:164-182
ISSN:1682-8658
Container-title:Experimental and Clinical Gastroenterology
language:
Short-container-title:ECG

Author:

Khavkin A. I.¹^ORCID,Nikolaychuk K. M.²^ORCID,Shrayner E. V.³^ORCID,Shaimardanova D. R.²^ORCID,Veremenko A. S.²^ORCID,Levchenko I. D.²^ORCID,Platonova P. Ya.²^ORCID,Novikova M. F.²^ORCID,Dudurich V. V.⁴^ORCID

Affiliation:

1. Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region; Belgorod State Research University

2. Novosibirsk State University

3. Novosibirsk State University; Institute of Chemical Biology and Fundamental Medicine of the SB RAS

4. ITMO National Research University; “Сerbalab” laboratory

Abstract

This work reviews current data on the structure of the microbiota and its interaction with the host, and assesses the impact of the microbial community on the immune system and the development of chronic inflammation in the gastrointestinal tract. This review presents current evidence on the influence of diet on the course and therapy of GI tract inflammation. Studies on the role of microbiota and diet in the pathogenesis of ICD have shown that microbial dysbiosis and Epstein-Barr virus can exacerbate the course of ICD. Certain foods worsen symptoms, while a monosaccharide diet favours remission. The results emphasise the importance of an individualised nutritional approach to improve the treatment of IBS.

Publisher

LLC Global Media Technology

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