Factors Predictive of Binaural Hearing Restoration by Cochlear Implant in Single-Sided Deafness

Abstract

<b><i>Introduction:</i></b> Cochlear implants (CIs) can restore binaural hearing in cases of single-sided deafness (SSD). However, studies with a high level of evidence in support of this phenomenon are lacking. The aim of this study is to analyze the effectiveness of CIs using several spatialized speech-in-noise tests and to identify potential predictors of successful surgery. <b><i>Methods:</i></b> Ten cases underwent standard CI surgery (MEDEL-Flex24). The speech-in-noise test was used in three different spatial configurations. The noise was presented from the front (N0), toward the CI (NCI), and toward the ear (Near), while the speech was always from the front (S0). For each test, the speech-to-noise ratio at 50% intelligibility (SNR50) was evaluated. Seven different effects were assessed (summation, head shadow [HS], speech released of masking [SRM], and squelch for the CI and for the ear). <b><i>Results:</i></b> A significant summation effect of 1.5 dB was observed. Contralateral PTA was positively correlated with S0N0-B and S0NCI-B (CIon and unplugged ear). S0N0-B results were positively correlated with S0N0-CIoff (<i>p</i> &lt; 0.0001) and with S0Near-CIoff results (<i>p</i> = 0.004). A significant positive correlation was found between delay post-activation and HS gain for the CI (<i>p</i> = 0.005). Finally, the HS was negatively correlated with the squelch effect for the ear. <b><i>Conclusion:</i></b> CI benefits patients with SSD in noise and can improve the threshold for detecting low-level noise. Contralateral PTA could predict good postoperative results. Simple tests performed preoperatively can predict the likelihood of surgical success in reversing SSD.