Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature-Reference-Cited by-同舟云学术

Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature

Published:2021 Issue:5 Volume:56 Page:482-491
ISSN:1016-2291
Container-title:Pediatric Neurosurgery
language:en
Short-container-title:Pediatr Neurosurg

Author:

Yue John K.,Chang Diana,Oh Taemin,Winkler Ethan A.,Lu Alex Y.,Hetts Steven W.^ORCID,Young Elizabeth P.,Reddy Alyssa T.,Fox Christine K.,Abla Adib A.,Roland Jarod L.^ORCID

Abstract

Introduction: Tumor-associated intracranial aneurysms are rare and not well understood. Case Presentation: We describe a 4-year-old female with multiple intracranial aneurysms intimately associated with a suprasellar germ cell tumor (GCT). We provide the clinical history, medical, and surgical treatment course, as well as a comprehensive and concise synthesis of the literature on tumor-associated aneurysms. Discussion: We discuss mechanisms for aneurysm formation with relevance to the current case, including cellular and paracrine signaling pertinent to suprasellar GCTs and possible molecular pathways involved. We review the complex multidisciplinary treatment required for complex tumor and cerebrovascular interactions.

Publisher

S. Karger AG

Subject

Neurology (clinical),General Medicine,Surgery,Pediatrics, Perinatology and Child Health

Reference37 articles.

1. Arieti S. Multiple meningioma and meningiomas associated with other brain tumors. J Neuropathol Exp Neurol. 1944;3(3):255–70.

2. Pia HW, Obrador S, Martin JG. Association of brain tumours and arterial intracranial aneurysms. Acta Neurochir. 1972;27(3):189–204.

3. Zhong Z, Sun Y, Lin D, Sun Q, Bian L. Surgical treatment of brain tumor coexisted with intracranial aneurysm case series and review of the literature. Neurosurg Rev. 2013 Oct;36(4):645–56.

4. Zee CS, Segall HD, McComb JG, Stanley P, Little FM, Ahmadi J, et al. Intracranial arterial aneurysms in childhood: more recent considerations. J Child Neurol. 1986 Apr;1(2):99–114.

5. Olmsted WW, McGee TP. The pathogenesis of peripheral aneurysms of the central nervous system: a subject review from the AFIP. Radiology. 1977 Jun;123(3):661–6.