Abstract
<b><i>Objectives:</i></b> The objectives of this study were to evaluate the diagnostic abilities of the cerebroplacental ratio (CPR) for the prediction of adverse perinatal outcome (APO) and cesarean section for intrapartum fetal compromise (CS-IFC) within 1 day of delivery. <b><i>Design:</i></b> Retrospective observational case-control study. <b><i>Methods:</i></b> This was a study of 254 high-risk fetuses attending the day hospital unit of a tertiary referral hospital that underwent an ultrasound examination at 32–41 weeks and gave birth within 1 day of examination. APO was defined as a composite of abnormal intrapartum fetal heart rate or intrapartum fetal scalp pH <7.20 requiring urgent cesarean section, neonatal umbilical cord pH <7.10, 5-min Apgar score <7, and postpartum admission to neonatal or pediatric intensive care units. CS-IFC was defined in case of abnormal intrapartum fetal heart rate or intrapartum fetal scalp pH <7.20 requiring urgent cesarean section. The diagnostic ability of CPR for the prediction of APO and CS-IFC was calculated alone and in combination with estimated fetal weight and gestational clinical parameters, including the type of labor onset, using ROC curves and logistic regression analysis. <b><i>Results:</i></b> CPR in multiples of the median (MoM) was a moderate predictor of APO (area under the curve [AUC] = 0.77, <i>p</i> < 0.0001) and CS-IFC (AUC = 0.82, <i>p</i> < 0.0001). The predictive abilities of the multivariable model for APO (AUC = 0.81, <i>p</i> < 0.0001) and CS-IFC (AUC = 0.82, <i>p</i> < 0.0001) did not differ from those of CPR alone . <b><i>Limitations:</i></b> The small number of cases and the scarcity of information concerning labor induction. <b><i>Conclusion:</i></b> In high-risk pregnancies, CPR MoM is a moderate predictor of APO and CS-IFC when performed within 24 h of delivery.
Subject
Obstetrics and Gynaecology,Reproductive Medicine