Author:
Ahmed Ashraf Omer Elamin,Elfert Khaled A.,Mahfouz Ahmed E.,Othman Fahmi S.,Elgassim Lenah A.,Yassin Mohamed A.
Abstract
Complete superior vena cava (SVC) and inferior vena cava (IVC) obstruction is not uncommon and most commonly associated with malignancy. The risk increases in patients with central lines and hypercoagulable states such as with malignancy, thrombophilia, or use of oral contraceptive pills. According to our knowledge, complete SVC and IVC obstruction associated with systemic-to-pulmonary venous shunts in patients with prothrombin G20210A gene mutation has not been reported in the literature. Here we report the case of a 34-year-old female with complete SVC and IVC obstruction presenting with oxygen desaturation and shortness of breath due to systemic-to-pulmonary venous shunts. The unusual collateral pathway was secondary to SVC obstruction. The patient was managed conservatively, and she remained stable.
Reference14 articles.
1. Wilson L, Detterbeck F, Yahalom J. Clinical practice. Superior vena cava syndrome with malignant causes. N Engl J Med. 2007;356(18):1862–9.
2. Sarecka-Hujar B, Kopyta I, Skrzypek M, Sordyl J. Association between the 20210G>A prothrombin gene polymorphism and arterial ischemic stroke in children and young adults – two meta-analyses of 3,586 cases and 6,440 control subjects in total. Pediatr Neurol. 2017;69:93–101.
3. Pickering W, Marriott K, Regan L. G20210A prothrombin gene mutation: prevalence in a recurrent miscarriage population. Clin Appl Thromb Hemost. 2001 Jan;7(1):25–8.
4. Shefler A, Gillis J, Lam A, O’Connell AJ, Schell D, Lammi A. Inferior vena cava thrombosis as a complication of femoral vein catheterisation. Arch Dis Child. 1995;72(4):343–5.
5. Dayan N, Holcroft C, Tagalakis V. The risk of venous thrombosis, including cerebral vein thrombosis, among women with thrombophilia and oral contraceptive use: a meta-analysis. Clin Appl Thromb Hemost. 2008 Nov;17(6):E141–52.
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献