GCAT-SEEKquence: Genome Consortium for Active Teaching of Undergraduates through Increased Faculty Access to Next-Generation Sequencing Data

Author:

Buonaccorsi Vincent P.1,Boyle Michael D.1,Grove Deborah2,Praul Craig2,Sakk Eric3,Stuart Ash4,Tobin Tammy5,Hosler Jay6,Carney Susan L.7,Engle Michael J.8,Overton Barry E.9,Newman Jeffrey D.10,Pizzorno Marie6,Powell Jennifer R.11,Trun Nancy12

Affiliation:

1. *Juniata College, Huntingdon, PA 16652

2. Pennsylvania State University, State College, PA 16802

3. Morgan State University, Baltimore, MD 21251

4. Ramapo College of New Jersey, Mahwah, NJ 07430

5. Susquehanna University, Selinsgrove, PA 17870

6. Bucknell University, Lewisburg, PA 17837

7. Hood College, Frederick, MD 21701

8. Mount Aloysius College, Cresson, PA 16630

9. Lock Haven University, Lock Haven, PA 17745

10. **Lycoming College, Williamsport, PA 17701

11. Gettysburg College, Gettysburg, PA 17325

12. Duquesne University, Pittsburgh, PA 15282

Abstract

To transform undergraduate biology education, faculty need to provide opportunities for students to engage in the process of science. The rise of research approaches using next-generation (NextGen) sequencing has been impressive, but incorporation of such approaches into the undergraduate curriculum remains a major challenge. In this paper, we report proceedings of a National Science Foundation–funded workshop held July 11–14, 2011, at Juniata College. The purpose of the workshop was to develop a regional research coordination network for undergraduate biology education (RCN/UBE). The network is collaborating with a genome-sequencing core facility located at Pennsylvania State University (University Park) to enable undergraduate students and faculty at small colleges to access state-of-the-art sequencing technology. We aim to create a database of references, protocols, and raw data related to NextGen sequencing, and to find innovative ways to reduce costs related to sequencing and bioinformatics analysis. It was agreed that our regional network for NextGen sequencing could operate more effectively if it were partnered with the Genome Consortium for Active Teaching (GCAT) as a new arm of that consortium, entitled GCAT-SEEK(quence). This step would also permit the approach to be replicated elsewhere.

Publisher

American Society for Cell Biology (ASCB)

Subject

General Biochemistry, Genetics and Molecular Biology,Education

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