COVID-19 a global crisis: Features, complications and suggested treatments

Abstract

<p><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: PMingLiU; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">Coronavirus disease&nbsp;2019 (COVID-19); caused by the novel coronavirus (SARS-CoV-2)&nbsp;is the talk of everyone all over the world in 2020 since it has been considered as a public health emergency of international concern by WHO in 30^th January, 2020. COVID-19 is a highly transmittable disease with different symptoms which can vary from mild to severe and life threatening. Scientists all over the world are working on finding a treatment or vaccine for this disease. All of these studies are currently not finished yet during writing this review. However, in this review a summary about the current status of these studies is given. This summary includes medicinal plants and natural products, antivirals like </span><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; color: #2e2e2e; mso-font-kerning: .5pt; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">remdesivir, favipiravir,</span><strong><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: PMingLiU; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;"> </span></strong><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; color: #2e2e2e; mso-font-kerning: .5pt; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">oseltamivir and nelfinavir as well as other miscellaneous drugs like chloroquine, hydroxychloroquine and ivermectin which showed promising results in treating COVID-19. In conclusion, the review recommends conducting further investigations worldwide and reporting them in peer-reviewed publications to aid in improving the drugs&rsquo; dosing regimens and clinical studies. </span></p>