Affiliation:
1. Department of biology, College of science for women, University of Babylon, Iraq
Abstract
Laboratory experiments were performed to study 66 samples were collected for
beta-thalassemia patients, with 30 samples for control of healthy people, male
and female, and 96 samples were examined in the Cobas e411 Advice for both
IgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected
with a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis
and 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the
relationship between Uric Acid and Allantoin, where the relationship is inverse
between them; in the case of infection and the presence of the parasite in the
blood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful
to the cell or tissue. Free radicals in abundance and as a guide to the extent of
damage performed by the parasite.
Keywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and
IgM.
Subject
Infectious Diseases,Applied Microbiology and Biotechnology,Epidemiology,Biotechnology
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