Differentiated approaches to the treatment of urinary tract infection in children taking into account the etiological factor Enterococcus faecalis-Reference-Cited by-同舟云学术

Differentiated approaches to the treatment of urinary tract infection in children taking into account the etiological factor Enterococcus faecalis

Published:2019-12-28 Issue:4 Volume: Page:60-65
ISSN:1609-1175
Container-title:Pacific Medical Journal
language:
Short-container-title:Tihookeanskij medicinskij žurnal

Author:

Melnikova E. A.¹^ORCID,Zaitseva E. A.²,Luchaninova V. N.³,Krukovich E. V.²,Komenkova T. S.²,Feoktistova Yu. V.¹

Affiliation:

1. Regional Children's Clinical Hospital No. 1; Pacific State Medical University

2. Pacific State Medical University

3. North-Western State Medical University named after I.I. Mechnikov

Abstract

Objective:The objective is to develop an algorithm of initial antimicrobial treatment of urinary tract infection (UTI) concidering the etiological factorEnterococcus faecalis, having spontaneous resistance to cephalosporins.Methods:The analysis of 6438 results of urine bacteriological examination of children with UTI, having received the treatment in multi-field children’s hospital for 9 years, and clinical manifestations of UTI associated withE. faecalisin 181 patients was carried out. Addirionally, antimicrobial susceptibility testing was carried out in 60 cultures ofE. faecalis.Results:E. faecalisis occurred to be the second etiological factor of UTI in order of importance in children and had high priority in its development in newborns. The detected diagnostic markers of UTI associated withE. faecalis, and its antimicrobial susceptibility are represented in the author-developed algorithm of the initial antimicrobial treatment.Conclusions:The algorithm of the initial antimicrobial treatment of UTI caused byE. faecaliswill help to prescribe a sustainable, early antimicrobial treatment at the stage of microbe identification.

Publisher

Pacific State Medical University

Subject

General Medicine

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