Myasthenia Gravis in the Neonate

Abstract

Myasthenia gravis (MG) in the neonate is usually an autoimmune disorder, although some neonates have congenital MG, which most commonly seems to be due to an autosomal recessive disorder. The most common form of MG in the neonate is transient and results from placentally transferred antibodies to acetylcholine. In this article, we review MG affecting both mothers and infants and use a case of transient neonatal MG to demonstrate the clinical features of the disorder. The infant was born to an apparently asymptomatic mother.