Rates and Stability of Mental Health Disorders in Children Born Very Preterm at 7 and 13 Years

Author:

Yates Rosemary12,Treyvaud Karli23,Doyle Lex W.2456,Ure Alexandra7289,Cheong Jeanie L.Y.245,Lee Katherine J.26,Inder Terrie E.10,Spencer-Smith Megan12,Anderson Peter J.12

Affiliation:

1. Turner Institute for Brain and Mental Health, School of Psychological Sciences and

2. Murdoch Children’s Research Institute, Parkville, Victoria, Australia;

3. Department of Psychology and Counselling, La Trobe University, Melbourne, Victoria, Australia;

4. Neonatal Services, The Royal Women’s Hospital, Parkville, Victoria, Australia;

5. Departments of Obstetrics and Gynaecology and

6. Paediatrics, The University of Melbourne, Parkville, Victoria, Australia;

7. Department of Paediatrics and Education Research, Monash University, Clayton, Victoria, Australia;

8. Department of Mental Health, The Royal Children’s Hospital, Parkville, Victoria, Australia;

9. Developmental Paediatrics, Monash Children's Hospital, Clayton, Victoria, Australia

10. Brigham and Women’s Hospital, Boston, Massachusetts; and

Abstract

OBJECTIVES: Children born very preterm (VPT) are at an increased risk of developing mental health (MH) disorders. Our aim for this study was to assess rates of MH disorders in children born VPT and term at 13 years of age and stability of MH disorders between ages 7 and 13 years by using a diagnostic measure. METHODS: Participants were from the Victorian Infant Brain Study longitudinal cohort and included 125 children born VPT (<30 weeks’ gestational age and/or <1250 g) and 49 children born term (≥37 weeks’ gestational age) and their families. Participants were followed-up at both 7 and 13 years, and the Development and Well-Being Assessment was administered to assess for MH disorders. RESULTS: Compared with term peers, 13-year-olds born VPT were more likely to meet criteria for any MH disorder (odds ratio 5.9; 95% confidence interval 1.71–20.03). Anxiety was the most common disorder in both groups (VPT = 14%; term = 4%), whereas attention-deficit/hyperactivity disorder carried the greatest differential elevated risk (odds ratio 5.6; 95% confidence interval 0.71–43.80). Overall rates of MH disorders remained stable between 7 and 13 years, although at an individual level, many participants shifted in or out of diagnostic categories over time. CONCLUSIONS: Children born VPT show higher rates of MH disorders than their term peers, with changing trajectories over time. Findings highlight the importance of early identification and ongoing assessment to support those with MH disorders in this population.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference32 articles.

1. Cognitive and educational deficits in children born extremely preterm;Anderson;Semin Perinatol,2008

2. Long term respiratory outcomes of very premature birth (<32 weeks);Greenough;Semin Fetal Neonatal Med,2012

3. Risk of developmental delay increases exponentially as gestational age of preterm infants decreases: a cohort study at age 4 years;Kerstjens;Dev Med Child Neurol,2012

4. Psychiatric disorders in extremely preterm children: longitudinal finding at age 11 years in the EPICure study;Johnson;J Am Acad Child Adolesc Psychiatry,2010

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