Critical Issues in Food Allergy: A National Academies Consensus Report

Author:

Sicherer Scott H.1,Allen Katrina23,Lack Gideon45,Taylor Steve L.6,Donovan Sharon M.7,Oria Maria8

Affiliation:

1. Division of Pediatric Allergy and Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, New York;

2. Centre for Food and Allergy Research, Murdoch Children’s Research Institute, The University of Melbourne, Victoria, Australia;

3. Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom;

4. Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, King’s College London, London, United Kingdom;

5. Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom;

6. Food Allergy Research and Resource Program, Department of Food Science and Technology, University of Nebraska, Lincoln, Nebraska;

7. Department of Food Science and Human Nutrition, University of Illinois, Urbana, Illinois; and

8. National Academies of Sciences, Engineering and Medicine, Washington, DC

Abstract

The National Academies of Sciences, Engineering, and Medicine convened an expert, ad hoc committee to examine critical issues related to food allergy. The authors of the resulting report, “Finding a Path to Safety in Food Allergy: Assessment of the Global Burden, Causes, Prevention, Management, and Public Policy,” evaluated the scientific evidence on the prevalence, diagnosis, prevention, and management of food allergy and made recommendations to bring about a safe environment for those affected. The committee recommended approaches to monitor prevalence, explore risk factors, improve diagnosis, and provide evidence-based health care. Regarding diagnostics, emphasis was placed on utilizing allergy tests judiciously in the context of the medical history because positive test results are not, in isolation, diagnostic. Evidence-based prevention strategies were advised (for example, a strategy to prevent peanut allergy through early dietary introduction). The report encourages improved education of stakeholders for recognizing and managing as well as preventing allergic reactions, including an emphasis on using intramuscular epinephrine promptly to treat anaphylaxis. The report recommends improved food allergen labeling and evaluation of the need for epinephrine autoinjectors with a dosage appropriate for infants. The committee recommended policies and guidelines to prevent and treat food allergic reactions in a various settings and suggested research priorities to address key questions about diagnostics, mechanisms, risk determinants, and management. Identifying safe and effective therapies is the ultimate goal. This article summarizes the key findings from the report and emphasizes recommendations for actions that are applicable to pediatricians and to the American Academy of Pediatrics.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

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