Hyperlipidemia in the Hemolytic-Uremic Syndrome

Abstract

Campbell and Carré1 recorded the occurrence of hypertriglyceridemia in association with fatal hemolytic-uremic syndrome in a set of monozygotic twins and suggested that the hypertriglyceridemia was present as an inherited disease. The purpose of this paper is to describe the finding of elevated triglyceride, cholesterol and phospholipid levels in six children with hemolytic-uremic syndrome. Materials and Methods Serum triglyceride, cholesterol, and phospholipid levels were measured in six out of seven consecutive patients with hemolyticuremic syndome admitted to the Transvaal Memorial Hospital for Children, Johannesburg. The criteria for diagnosis were hemolytic anemia with fragmentation of the red cells, a platelet count below 140,000 per cmm, and evidence of renal involvement.