Paraneoplastic Autoimmune Multiorgan Syndrome (Paraneoplastic Pemphigus) in a Child: Case Report and Review of the Literature-Reference-Cited by-同舟云学术

Paraneoplastic Autoimmune Multiorgan Syndrome (Paraneoplastic Pemphigus) in a Child: Case Report and Review of the Literature

Published:2004-10-01 Issue:4 Volume:114 Page:e513-e516
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Lane Joshua E.¹,Woody Carol¹,Davis Loretta S.¹,Guill Margaret F.²,Jerath Rita S.³

Affiliation:

1. Section of Dermatology, Department of Medicine

2. Section of Pulmonology, Department of Pediatrics

3. Section of Rheumatology, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia

Abstract

Paraneoplastic autoimmune multiorgan syndrome, also known as paraneoplastic pemphigus, has been observed only rarely among children. We describe a 10-year-old boy with typical clinical and histologic findings of paraneoplastic pemphigus associated with Castleman’s disease. His disease was refractory to resection of the tumor and aggressive combination immunosuppressive therapies. The patient died 1 year after presentation, as a result of complications of bronchiolitis obliterans. This case is unusual because of the young age of the patient.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/114/4/e513/1019939/zpe0100400e513.pdf

Reference28 articles.

1. Anhalt GJ, Kim SC, Stanley JR, et al. Paraneoplastic pemphigus: an autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med. 1990;323:1729–1735

2. Borradori L, Lombardi T, Samson J, Girardet C, Saurat JH, Hugli A. Anit-CD20 monoclonal antibody (rituximab) for refractory erosive stomatitis secondary to CD20+ follicular lymphoma-associated paraneoplastic pemphigus. Arch Dermatol. 2001;137:269–272

3. Heizmann M, Itin P, Wernli M, Borradori L, Bargetzi MJ. Successful treatment of paraneoplastic pemphigus in follicular NHL with rituximab: report of a case and review of treatment for paraneoplastic pemphigus in NHL and CLL. Am J Hematol. 2001;66:142–144

4. Kiyokawa C. Envoplakin and periplakin and the paraneoplastic pemphigus antigens. Kurume Med J. 1999;46:71–78

5. Mahoney MG, Aho S, Uitto J, Stanley JR. The members of the plakin family of proteins recognized by paraneoplastic pemphigus. J Invest Dermatol. 1998;111:308–313

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Paraneoplastic pemphigus presenting as a prodrome to aggressive T cell lymphoma;BMJ Case Reports;2024-06

2. Paraneoplastic pemphigus and Castleman’s disease: a case report and a revision of the literature;Italian Journal of Pediatrics;2023-03-20

3. Paraneoplastic pemphigus associated with Castleman's disease;Journal of Paediatrics and Child Health;2023-01-30

4. Clinical and Pathological Characteristics of Hyaline-Vascular Type Unicentric Castleman Disease: A 20-Year Retrospective Analysis;Diagnostics;2021-10-28

5. Paraneoplastic autoimmune multiorgan syndrome;Italian Journal of Dermatology and Venereology;2021-05